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REVIEW ARTICLE
Year : 2017  |  Volume : 6  |  Issue : 6  |  Page : 241-244

Research progress of transfering mitochondria application in nanotubes in treatment of acute lung injury sepsis


1 Hainan Medical University, 3 Xueyuan Rd, Longhua District, Haikou City, Hainan Province, 570000, China
2 Hainan Medical University, 3 Xueyuan Rd, Longhua District, Haikou City, Hainan Province, 570000; Emergency Department, The First Affiliated Hospital of Hainan Medical University, Haikou, Hainan, 570100, China

Correspondence Address:
Xiao-Ran Liu
Emergency Department, The First Affiliated Hospital of Hainan Medical University, 31 Longhua Road, Haikou, Hainan
China
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2221-6189.221286

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Acute lung injury (ALI) is a common complication of sepsis with characteristics of acute onset, rapid change in the disease and high mortality. Since current clinical treatment can only alleviate the unfavorable condition to a certain extent but cure, we urgently need to find an effective treatment. Most scholars believe that sepsis-induced ALI is associated with extensive mitochondrial damage. In recent years, a widely studied pluripotent stem cell that is mesenchymal stem cell has been proved to alleviate and treat sepsis-induced ALI by transporting mitochondria via nanotubes in a microtubule-dependent manner. Research progress in this field will be reviewed in this study.


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